transport diversity across the fungal kingdom

Fungi are ideal organisms for studying intracellular transport diversification as they exhibit a wide range of phenotypic diversity, include species known to use actin- and/or microtubule-dependent transport, and encompass many species that are already genetically tractable. Our lab uses comparative genomics to identify transport-related genes encoded in the genomes of different fungi to generate hypotheses concerning intracellular transport adaptation in different contexts. We then use comparative cell biology in different fungal species to directly test these hypotheses.

Dynein (green) and nuclei (magenta) in the filamentous fungus Aspergillus nidulans.